
NY TImes Bestselling Author
Dave Asprey
“There is a more powerful form of copper that is associated with antiaging. Scientists have discovered that copper can be bound to a B vitamin called niacin that increases blood flow. The patented combination, called BioCopper1 (Cunermuspir), from a company called MitoSynergy is profoundly effective.”
- Dave Asprey, Smarter Not Harder
Re-Pigmentation Starts At The Roots
If you are wondering why your hair is going gray, the answer often lies in a specific gray hair vitamin deficiency. Inside your hair follicles, an enzyme called tyrosinase works to convert amino acids into melanin—the pigment that gives your hair its natural, youthful color.
However, tyrosinase cannot function on its own. Bioavailable copper 1 plays a crucial role in activating tyrosinase. Without adequate, usable copper at the cellular level, melanocytes struggle to produce melanin molecules as the hair grows. Providing your body with the copper it needs to activate tyros

Upgrade Your Mitochondria to Help the Body Help Itself
Healthy hair growth requires massive amounts of cellular energy. Human energy boils down to a form of currency called ATP (adenosine triphosphate), which powers every function that the body performs, including the active transport of nutrients into cells and the removal of cellular waste.
The greatest yield of ATP—about 90%—is found in the electron transport chain. This chain requires bioavailable copper (I) to operate. Only MitoSynergy provides bioavailable copper 1 fuel your mitochondria can use to support sustained energy, mental clarity, and cellular health.
Finding the Right Supplement for Gray Hair
Whether you are looking to help with symptoms of early graying or wanting targeted hair restoration, our BioCopper1 line offers a solution. For best results, separate your BioCopper1 doses by a few hours (morning and evening). Gray hair will begin to change at the roots.
Targeted Hair Formulations
Grow + Restore Cu1: Our flagship, comprehensive hair growth supplement formulated for both thinning hair and gray reversal. (Link to flagship product page)
Restore Cu1: A targeted, all-herbal formulation containing high-level copper strictly for gray hair support, without the thickening agents.
Core BioCopper1 Formulas
MitoActivator MAX (2.0mg BioCopper1 per capsule): If you wish to actively support gray hair reversal from the inside out, take 1-4 capsules daily (2-8mg).
Scanning electron microscope image of BioCopper1
Clinical Data for BioCopper1
Impact of Medical Symptoms on Subject’s Daily Life
A randomized, double-blind, placebo controlled, parallel study evaluated the efficacy of BioCopper1 on energy, strength, fatigue, and discomfort in subjects with nerve or muscle pain.
The primary objective of this study conducted on subjects with unresolved persistent muscle or nerve pain was to examine the effect of BioCopper1 on quality of life. Secondary objectives of the study were to determine changes from baseline in physical function, pain, and fatigue/energy.

Improvements in the impact of muscle and nerve pain symptoms on subject’s daily life per protocol participants supplemented with placebo or Cunermuspir. N = 25 and 24 for placebo and Cunermuspir, respectively. P values correspond to between group comparisons.
Real Results from the MitoSynergy Community
Gray hair reversal dosing guide
- If you are just beginning to see gray hair: Start with 2 MitoActivator EX daily. Increase as needed.
- If you wish to reverse gray hair: 1-4 MitoActivator MAX capsules daily (2-8mg)
For best results, separate BioCopper1 doses by a few hours. We suggest morning and evening. Gray hair will begin to change at the roots.
| Product | Serving size | mg of BioCopper1 |
|---|---|---|
| BioCopper1 Supplements | ||
| MitoActivator LDS | 1 capsule | .10 |
| MitoActivator EX | 1 capsule | .50 |
| MitoActivator MAX | 1 capsule | 2 |
| Multi-Vitamins | ||
| MitoSynergy Original | 1 capsule | .25 |
| MitoAdvanced | 4 capsules | 2 |
New to MitoSynergy BioCopper1? Here’s What You Should Know

Heat and humidity
BioCopper1 is sensitive to heat and humidity, so proper storage is essential to maintain the integrity of the formula. Please store in a cool, dark place (NOT the refrigerator) and always replace the desiccant pack that absorbs moisture. The moisture from your skin may contaminate the capsules, so only pour one dose at a time into the bottle cap.
Exposure to heat, humidity, or moisture can compromise the effectiveness of copper supplements. You’ll know the capsules have been contaminated if their color changes from orange to a blue tint - this indicates they have oxidized and should not be consumed.Proper storage ensures that your copper supplement remains safe, potent, and beneficial for supporting your health.

Anti-microbial
BioCopper1 is not only a source of energy - it’s also a powerful anti-bacterial and anti-microbial compound. As your body begins to absorb and use this highly bioavailable form of copper, you may experience what’s known as a Herxheimer reaction (or "herx" reaction). This temporary response occurs when copper supplements help the body eliminate unwanted bacteria, viruses, or other microbial imbalances, leading to short-term symptoms like fatigue, headache, or mild discomfort.
While this process can feel unpleasant, it’s often a sign that the supplement is working to support your body's natural detoxification systems. If you notice these effects, we recommend starting with a lower dose of BioCopper1 and gradually increasing until you can comfortably tolerate the full amount.
Taking copper supplements as part of your wellness routine may not only promote energy production within the body but also help support a cleaner internal environment, supporting both immune resilience and overall health from within.
For anti-aging
Which product should I start with?
Most people take this
for maximum anti-aging including reduction of gray hair†
MitoActivator MAX
2 mg BioCopper1
per capsule
If you are just beginning to see gray hair, start with 1 MitoActivator MAX daily; increase as needed. If you wish to reverse gray hair, 1-4 MitoActivator MAX capsules daily (2-8mg)
EX is a great place to start if you are unsure of how much copper you need.
MitoActivator EX
.5 mg BioCopper1
per capsule
Start with 1 and work up to 3-4 a day.
MitoAdvanced is our multi-nutrient complex for optimum anti-aging effect.†
MitoAdvanced
2 mg BioCopper1
per 4 capsules
We recommend taking MitoAdvanced if you are looking for a multivitamin with Mitochondrial support. Start with 1 a day and work your way up to 4 a day.
Testimonials
If you are new to MitoSynergy BioCopper1 supplements, there are a couple of things you need to know.
BioCopper1 is sensitive to heat and humidity. Please store in a cool, dark place (NOT the refrigerator). Always replace the desiccant pack that absorbs moisture. The moisture from your skin may contaminate the capsules so only pour one dose at a time into the bottle cap. Capsules are contaminated when their color changes from orange to a blue tint, indicating they are oxidized.
BioCopper1 is a powerful anti-bacterial and anti-microbial compound that may cause a herx reaction. This means that the BioCopper1 will not only help your body make more energy, but it may also help eliminate unwanted bacteria and viruses living in your body. That process may cause you to feel temporarily unwell. If that happens, we suggest starting with a lower dose and slowly increasing until you tolerate the full dose.
















